VAXIGRIP SANOFI | Indication, Contraindication And How Given

VAXIGRIP SANOFI | Indication, Contraindication And How Given

VAXIGRIP SANOFI is a vaccine manufactured by Sanofi International Company that helps to protect the body against the influenza virus.

It should be used according to official recommendations.

When VAXIGRIP SANOFI has been injected, the body's defence system (immune system) produces antibodies against 3 strains of the influenza virus after about 2-3 weeks after injection but influenza can be caused by different versions of virus strains that can be changed every year, So scientists try to predict the strains that will be most likely for the coming year and using them to make up the year's influenza vaccine, so the body needs to be vaccinated each year.

The incubation period of the influenza virus is a few days, so if the body is exposed to the flu immediately after or before the injection of the vaccine, the disease is still developed.

This vaccine protects against flu from 6to 12 months, but may not fully protect all persons who are vaccinated.

Contraindication Of Giving VAXIGRIP SANOFI :

1-If the patient is allergic to

-                The active substances or any trace products found in this vaccine.

-                Any component such as eggs, neomycin, formaldehyde or octoxinol-9.

2-If a patient has an acute infection or an illness with a high temperature, the vaccination should be postponed until the patient has recovered.

The National Advisory Committee on Immunisation recommends annual vaccination for :

-The medical staff or family members are at high risk.

-People over 65 years of age and healthy children aged 6 to 59 months.

-Adults and children who have chronic disorders of the cardiovascular system or the pulmonary system.

-Patients with Diabetic Mellitus, renal dysfunction, haemoglobinopathies or immunosuppression.

-Children aged 6 months to 18 years who are receiving long-term aspirin therapy because of the risk for developing Reye syndrome after influenza.

In Case Of Pregnancy And Breast-Feeding :

The doctor should be consulted before vaccination in case of pregnancy or planning to have a baby and he can decide if she should receive VAXIGRIP SANOFI.

In case there is no problem to take in pregnancy, it can be used at all stages of pregnancy, but it is better to be used in the second and the third trimester.

It may be used during breastfeeding after doctor consultation and the NACI states this vaccine is considered safe for nursing women.

In Case Of Neurological Disorders:

In this case, vaccination should be delayed till the disease process has been stabilized because Guillain-Barre` syndrome has been reported after influenza vaccination.

Therefore, the NACI and APCI avoid giving the vaccine to persons who are known to have experienced GBS within 6 to 8 weeks after previous influenza vaccination.

Before Vaccination, patients should take into consideration that the patient should tell the doctor if has a poor immune response or bleeding problem or bruising easily and the doctor will decide what should be done before vaccination.

Are there side effects for VAXIGRIP SANOFI?

Yes, VAXIGRIP SANOFI may show side effects

These side effects have been reported by at least 1% of people after vaccination and many of these can be managed or may go away over time.

The most common side effects in adults and the elderly are :

-Headache

-Muscle pain

-Injection site reaction as -redness, itching, pain or swelling.

-Malaise

-Unusual tiredness or weakness.

The most common side effects in pediatric patients are :

-Muscle pain

-Diarrhoea

-Loss of appetite

-Drowsiness

-Fever, malaise

-Vomiting

-Insomnia

-Dizziness

But some rare side effects may affect up to 1 in 1000 people such as allergic reactions, numbness, paresthesia, hypoesthesia or archival radiculitis or swelling of the glands in the neck, groin or armpit.

Rare allergic reactions are characterized by skin reactions that spread throughout the body including itching, hives, rash or erythema.

But in case a severe allergic reaction occurs with low blood pressure, rapid breathing, rapid heart rate and weak pulse that may lead to shock, the patient should see the doctor immediately.

Uncommon side effects affect adults and elderly patients:

-Sleepiness, dizziness

-Flu-like syndrome

-Discomfort and warmth at the injection site.

Uncommon side effects in pediatric patients:

-Swelling of the glands in the neck or groin.

-Haemorrhage and warmth at the site injection.

All of these side effects usually occur within 3 days after vaccination and disappear within 1 to 3 days when side effects are mild or moderate, but if any of these gets serious, the patient should see the doctor.

How can VAXIGRIP SANOFI be given?

It is given as an injection into the tissue below the skin of the upper arm or the muscle or legs in infants and shouldn't be injected into the veins.

Dosage :

It is suspension for injection in a prefilled syringe of 0.25ml or 0.5ml

-Children aged 6 to 35 months take a single dose (,25 ).

-Children over 36 months and adults take a single dose (,5ml).

Sometimes, some children need a second injection a month later as a child aged less than 9 years and has not been vaccinated previously against influenza, so should take a second dose after 4 weeks and eligible children less than 9 years who have received one or more doses of TIV in the past are recommended to receive one dose per season.

VAXIGRIP SANOFI should be given annually.

Precautions :

This vaccine should be kept away from children.

It should be kept in its original pack till it's time to be given.

It should be kept in the refrigerator between 2°c and 8°c and away from light.

Don't freeze it because freezing destroys the vaccine.

The vaccine should be brought to room temperature before injection.

It shouldn't be mixed with other medicines in the same syringe, but it can be given at the same time with other vaccines by using separate limbs and under doctor consultation.

As well as all injectable vaccines, epinephrine hydrochloride solution and other appropriate medical treatment and supervision should be available readily for immediate use in case anaphylactic shock or hypersensitivity reaction occurs, although it is rare.

Product Information :

-It is manufactured by Sanofi Pasteur SA (Lyon, France ).

-It is distributed by Toronto, Ontario, Canada.