مؤسسة الشرق الأوسط للنشر العلمي
عادةً ما يتم الرد في غضون خمس دقائق
Gingival tissue is essential for maintaining oral health by providing structural support and acting as a barrier against microbial threats. This study performs a comparative analysis of gingival tissue properties in healthy individuals versus those with periodontal disease. Healthy gingival tissue is firm, resilient, and resists inflammation, preserving the integrity of the alveolar bone and periodontal ligaments. In contrast, periodontal disease induces chronic inflammation, leading to significant edema, collagen degradation, and increased infiltration of immune cells such as neutrophils and macrophages. These changes weaken gingival structure, compromising connective tissue and accelerating disease progression. The dysbiosis of the oral microbiome, driven by pathogens like Porphyromonas gingivalis, triggers an exaggerated immune response, creating a cycle of chronic inflammation and tissue destruction. This study employs histological and microbiological analyses to elucidate these alterations. By highlighting the distinct characteristics of gingival tissue in health and disease, the findings support the development of targeted therapies aimed at reducing tissue damage and promoting periodontal regeneration. Ultimately, this research advances clinical practices in periodontology and contributes to improved patient outcomes.