The Role of Inflammation in the Severity of Anemia in CKD Patients

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الإصدار الخامس والعشرون: 06 مارس 2025
من مجلة الشرق الأوسط للنشر العلمي

The Role of Inflammation in the Severity of Anemia in CKD Patients

Elhadi Altumi Shaeb
Abstract

Chronic Kidney Disease (CKD) is a significant global health challenge, with anemia being one of its most common complications. Inflammation has been identified as a key factor that exacerbates the severity of anemia in CKD through mechanisms such as impaired iron metabolism, increased hepcidin production, and reduced responsiveness to erythropoiesis-stimulating agents (ESAs). This paper provides a comprehensive review of the role of inflammation in the progression of anemia in CKD patients, highlighting key inflammatory markers and mechanisms. By synthesizing findings from recent studies, it emphasizes the need for targeted anti-inflammatory strategies to improve anemia outcomes in CKD patients.

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